PhosphoSolutions – Antibody Manufacture

Name: PhosphoSolutions

Location: Aurora, Colorado, USA.

What do you do? PhosphoSolutions is a biotechnology company. It was founded in 2001 by three scientists who met working in Nobel Laurate Paul Greengard’s lab at Rockefeller University, NY. We manufacture antibodies, which are unique research tools created to identify and bind to specific proteins or even specific areas of proteins. Proteins are the building blocks of the cell and as such antibodies are used in research for all sorts of experiment. For example, antibodies can be used to evaluate the effects of new drugs on a protein(s) known to be involved in disease or even to identify new drug targets.

Our specialty is producing phospho-specific antibodies. This antibodies recognize when a specific part of a protein has been phosphorylated (the addition of a phosphate group). Phosphorylation regulates the activity of the protein, essentially turning the protein on and off. Therefore, “Phospho-specific” antibodies do more than simply detect the presence of the protein; they indicate whether the protein is active or inactive. This provides a critical component for experiments designed to affect a target protein’s activity.

Our previous experience working in research allows us to develop procedures that produce antibodies of extremely high quality and reproducibility. To date we provide antibodies for all sorts of studies looking at things like signalling pathways, proteins in disease states like Alzheimer’s, Parkinson’s disease, and schizophrenia, in addition to proteins expressed in many cell lines and tissues. We also provide a custom antibody service to researchers for developing antibodies towards newly discovered targets.

What can you see? The parking lot for our building and Hole #1 of Fitzsimons Golf Course. We are located in the Colorado BioScience Park in Aurora, Colorado. This is on the grounds of the former Fitzsimons Army Medical Hospital which was closed in 1999 and subsequently redeveloped into what is now the University of Colorado’s Anschutz Medical Campus and the Fitzsimons Life Science District. The golf course is one of the last hold outs on campus from the original Army base and is slated for closure later this year to be developed into an additional Bioscience buildings and more residential apartments.

When I’m not doing science I like…Golfing, cooking, exploring the great outdoors, skiing/snowboarding, and spending quality time with friends and family.

If you’d like to find out more about PhosphoSolutions you have a look at their website (www.phosphosolutions.com) find them on Facebook (www.facebook.com/PhosphoSolutions), LinkedIn (www.linkedin.com/company/phosphosolutions) , or follow them on Instagram (www.instagram.com/phosphosolutions/).